Outcomes of progranulin gene therapy in the retina are dependent on time and route of delivery: Molecular Therapy - Methods & Clinical Development
Schematic diagram of the progranulin (PGRN) mechanism in HUVECs.... | Download Scientific Diagram
PGRN inhibits IFN-γ and TNFα activated gene expression of CXCL9 and... | Download Scientific Diagram
The lysosomal function of progranulin, a guardian against neurodegeneration. - Abstract - Europe PMC
Progranulin as a therapeutic target in neurodegenerative diseases: Trends in Pharmacological Sciences
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses | Life Science Alliance
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice | EMBO reports
Research Summary | The Hu Lab
Progranulin deficiency leads to reduced glucocerebrosidase activity | PLOS ONE
Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology | Acta Neuropathologica Communications | Full Text
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses | Life Science Alliance
Cells | Free Full-Text | Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases
Frontiers | Granulin in Frontotemporal Lobar Degeneration: Molecular Mechanisms of the Disease
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations | eNeuro
Frontiers | Progranulin Adsorbs to Polypropylene Tubes and Disrupts Functional Assays: Implications for Research, Biomarker Studies, and Therapeutics
Progranulin in frontotemporal lobar degeneration and neuroinflammation | Journal of Neuroinflammation | Full Text
Progranulin attenuates liver fibrosis by downregulating the inflammatory response | Cell Death & Disease
Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency - ScienceDirect
GRN-related Frontotemporal dementia (GRN-FTD)
Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects - ScienceDirect
Microorganisms | Free Full-Text | Association of Progranulin Gene Expression from Dyspeptic Patients with Virulent Helicobacter pylori Strains; In Vivo Model
The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C - Zhou - 2017 - Journal of Neurochemistry - Wiley Online Library
PGRN mutations identified in FTLD patients. Schematic representation of... | Download Scientific Diagram
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia: Trends in Cell Biology
Progranulin – Marker of Neuroinflammation | Biomol Blog | Resources | Biomol GmbH - Life Science Shop
